Oak Park Vocational High School, located at this site, opened in September, 1928. Based on the pattern of Tuskegee Institute, the school provided academic, vocational and agriculture education to African American students and included faculty housing and dormitories.
A fire destroyed most of the school complex in 1957. A new Oak Park High School building was constructed the following year.
Among the school's graduates are Ralph Boston, an Olympic gold medalist in the long jump and world-renowned opera singer Leontyne Price.